Preheat the oven to 375°F (190°C). Line a baking sheet with parchment paper and set aside.
Season the chicken wings on both sides with salt and pepper.
Arrange the wings in a single layer on a large roasting or baking pan. If necessary, use two pans to avoid overcrowding.
Bake the chicken wings for about 45 minutes, turning once halfway through, until browned and cooked through.
While the wings are baking, prepare the BBQ sauce mixture. In a small bowl, whisk together the BBQ sauce, honey, garlic powder, onion powder, salt, and pepper.
Once the wings are cooked, remove them from the oven and pour off any excess fat from the pan. If needed, blot the wings with paper towels to remove any excess grease.
Transfer the wings to a large bowl and pour the BBQ sauce mixture over them. Use your hands or tongs to coat the wings evenly with the sauce.
Place the sauced wings back onto the prepared baking sheet in a single layer.
Bake the wings for an additional 10 minutes, then turn them over and bake for another 10 minutes to ensure they are evenly coated and crispy.
Serve the Baked BBQ Chicken Wings hot, at room temperature, or even cold, with your favorite dipping sauce on the side.