Preheat your air fryer to 400°F.
In a bowl, mix together the flour, garlic powder, onion powder, smoked paprika, cayenne pepper, salt, and black pepper.
In another bowl, beat the eggs.
Place the panko bread crumbs in a third bowl.
Coat each chicken piece in the flour mixture, then dip in the beaten eggs, and finally coat in the panko bread crumbs.
Place the coated chicken pieces in the air fryer basket in a single layer.
Spray the chicken with cooking spray to help it crisp up.
Air fry the chicken bites for 8-10 minutes, flipping halfway through, until they are golden brown and cooked through.
Serve hot with your favorite dipping sauce.